In my research, I found that like with any natural. The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9. A man in Massachusetts died after eating too much black licorice, which contains a compound known to be toxic in large doses, according to a new report. Paeoniflorin's. Am J Chin Med 1996;24:165-8. Effects of the licorice extract against tumor growth and cisplatin-induced toxicity in a mouse xenograft model of colon cancer. Biol Pharm Bull. Exp Ther Med 2016;11(3):1135-41. View abstract. Takahara T, Watanabe A, Shiraki K. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. J Clin Ther Med 1999;15:499-523. View abstract. B. and Tang, T. Q. Goultschin, J., Palmon, S., Shapira, L., Brayer, L., and Gedalia, I. Celik, M. M., Karakus, A., Zeren, C., Demir, M., Bayarogullari, H., Duru, M., and Al, M. Licorice induced hypokalemia, edema, and thrombocytopenia. Zhang YD, Lorenzo B, Reidenberg MM. Brouwers, A. J. and van der, Meulen J. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. View abstract. Nephol Dial Transplant 1999;14:218-20. View abstract. 2019;33(1):117-29. Zhongguo Zhong Xi Yi Jie He Za Zhi. This fragrant, perennial plant -- a member of the celery family -- has smooth purplish stems and umbrella-shaped clusters of white flowers and winged fruits in July and August. Tsuda T, Sugaya A, Ohguchi H, et al. World J Gastroenterol 2005;11:2124-9. . View abstract. ['Licorice hypertension' also caused by licorice tea]. Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori. Licorice seems to change hormone levels in the body. 2019;18(Suppl1):291-301. View abstract. Dobbins, K. R. and Saul, R. F. Transient visual loss after licorice ingestion. [Effect of fu-zheng qu-xie on gastric disease infected with Campylobacter pyloridis]. Pontefract cakes can be bad for you: refractory hypertension and liquorice excess. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. A randomized, crossover comparison of herbal medicine and bromocriptine against risperidone-induced hyperprolactinemia in patients with schizophrenia. Postgrad Med J 2003;79:115-6.. View abstract. Endocrinol Jpn 1990;37:331-41. The effects of dietary licorice flavonoid oil supplementation on body balance control in healthy middle-aged and older Japanese women undergoing a physical exercise intervention: a randomized, double-blind, placebo-controlled trial. View abstract. Migraine is a type of headache. 1999;15:499-523. 1. Medicine (Baltimore) 2019;98(35):e16601. Acharya SK, Dasarathy S, Tandon A, et al. View abstract. Mohire, N. C. and Yadav, A. V. Chitosan-based polyherbal toothpaste: as novel oral hygiene product. Bocker, D. and Breithardt, G. [Induction of arrhythmia by licorice abuse]. Jafari Z, Emtiazy M, Sohrabvand F, et al. Licorice might increase how quickly the body breaks down paclitaxel. View abstract. View abstract. Some medications are changed and broken down by the liver. Fuhrman, B., Volkova, N., Kaplan, M., Presser, D., Attias, J., Hayek, T., and Aviram, M. Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressure. Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora. The combination of licorice and white peony can help to decrease the excess testosterone that is being produced by the ovaries in PCOS. [Severe hypokalemia after holidays return]. Therapeutic Research Faculty 2020. Kang, J. H., Park, Y. H., Choi, S. W., Yang, E. K., and Lee, W. J. Resveratrol derivatives potently induce apoptosis in human promyelocytic leukemia cells. "Water pills" can also decrease potassium levels. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection. No side effects or changes in liver function tests occurred during the study. I. Elucidation of five new flavonoid constituents from the roots of Glycyrrhiza glabra L. collected in Xinjiang. Mayo Clin Proc 2003;78:767-8. Chen MF, Shimada F, Kato H, Yano S, Kanaoka M. Effect of glycyrrhizin on the pharmacokinetics of prednisolone following low dosage of prednisolone hemisuccinate. Medically reviewed by Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT By Kirsten Nunez on October 16, 2020. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. Clinical and immunological consequences of total glucosides of paeony treatment in Sjgren's syndrome: A randomized controlled pilot trial. J Assoc Physicians India 1978;26(9):811-814. View abstract. Taking licorice with paclitaxel might decrease the effects of paclitaxel. Sun, W. S., Imai, A., Tagami, K., Sugiyama, M., Furui, T., and Tamaya, T. In vitro stimulation of granulosa cells by a combination of different active ingredients of unkei-to. Health Care Women Int. View abstract. Gender may affect the action of garlic oil on plasma cholesterol and glucose levels of normal subjects. Gut 1969;10:299-302. Caradonna, P., Gentiloni, N., Servidei, S., Perrone, G. A., Greco, A. V., and Russo, M. A. Licorice is believed to have anti-androgenic effects, meaning that it may be active to reduce testosterone levels. View abstract. Z. However, when Angelica Sinensis was tested in combination with products containing other substances, its activity was reduced. Apparent mineralcorticoid excess syndrome, an often forgotten or unrecognized cause of hypokalemia and hypertension: case report and appraisal of the pathophysiology. Mu Y, Zhang J, Zhang S, et al. View abstract. Am J Nephrol 2000;20:145-8. Sakamoto, S., Yoshino, H., Shirahata, Y., Shimodairo, K., and Okamoto, R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. J Ethnopharmacol 2021;275:114116. J Clin Endocrinol Metab 2003;88:2384-92. 2000;20(1):38-41. View abstract. View abstract. (Glycyrrhiza glabra), it performs better, especially for relaxing muscles, reducing painful menstruation, as well as lowering serum and free testosterone levels in women with PCOS. Zhongguo Zhong Xi Yi Jie He Za Zhi 2008;28(4):314-317. Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Effects of the Japanese herbal medicine "Sho-saiko-to" (TJ-9) on in vitro interleukin-10 production by peripheral blood mononuclear cells of patients with chronic hepatitis C. Hepatology 1997;25(6):1390-1397. View abstract. Clinical reduction of S. mutans in pre-school children using a novel liquorice root extract lollipop: a pilot study. Traditionally, white peony root is used for treating a wide range of health ailments, like inflammation, pain, and many more. Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Inflammopharmacology 2022;30(2):477-486. Kinoshita, H., Okabayashi, M., Kaneko, M., Yasuda, M., Abe, K., Machida, A., Ohkubo, T., Kamata, T., and Yakushiji, F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. 2017 Sep;31(9):1330-1340. Dong quai grows at high altitudes in the cold, damp, mountains of China, Korea, and Japan. J Clin Pharm Ther 2002;27:229-30. . 2020;50:102401. View abstract. The sweet stuff in your kids' trick-or-treat buckets may come with a bitter side effect. Most clinical trials have found that when Peony is combined with Licorice Rt. Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials. ""- . Chin J Integr Med 2022. Am J Chin Med 2005;33(5):747-758. View abstract. Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. Liu X, Li X, Li X, et al. Zhou, Y., Huang, Z., and Huang, T. [Clinical study of shengxue mixture in treating aplastic anemia]. 1991;4(2):166-173. 30. Cassano, N., Mantegazza, R., Battaglini, S., Apruzzi, D., Loconsole, F., and Vena, G. A. Anti Erection Pill. Horm.Res 1999;52(5):253-255. View abstract. View abstract. BMJ 1997;314:731-2. 2004;24(12):1084-1086. View abstract. N Engl J Med 1968;278(25):1381-1383. Since the content of glycyrrhizin is either decreased or removed from the DGL licorice supplement, its positive effects on PCOS may also be reduced. No negative side effects. Steroids 2004;69(11-12):763-766. Bernardi, M., D'Intino, P. E., Trevisani, F., Cantelli-Forti, G., Raggi, M. A., Turchetto, E., and Gasbarrini, G. Effects of prolonged ingestion of graded doses of licorice by healthy volunteers. View abstract. "It contains liquiritin, an active compound that helps to disperse and remove existing melanin in the skin," explains Chwalek. View abstract. American Herbal Products Association's Botanical Safety Handbook, Second Edition. Pseudohyperaldosteronism, liquorice, and hypertension. World J Gastroenterol 2-7-2006;12(5):760-764. Serra, A., Uehlinger, D. E., Ferrari, P., Dick, B., Frey, B. M., Frey, F. J., and Vogt, B. Glycyrrhetinic Acid decreases plasma potassium concentrations in patients with anuria. For people who already have high blood pressure or heart or kidney disease, as little as 5 g/day can cause these side effects. View abstract. J Clin Endocrinol Metab 1990;70(6):1637-1643. In 1977, researchers reported the case of a 58-year-old woman who was eating a whopping 1.8 kilograms (about 63.5 ounces) of black licorice per week and went into cardiac arrest. Acta Endocrinol (Buchar) 2020;16(4):508-510. View abstract. Drug Metab Dispos 2015;43(7):1147-53. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Phytotherapy Research 1997;11:207-210. van Gelderen, C. E., Bijlsma, J. Case Rep Emerg Med. [RETRACTED]. Dying for a cup of tea. Practitioner 1973;210:820-3. Peony might slow blood clotting. Guo TL, Zhou XW. View abstract. Total glucosides of peony ameliorates Sjogren's syndrome by affecting Th1/Th2 cytokine balance. Clin Exp Obstet Gynecol 2013;40(1):141-143. Contact Dermatitis 1999;40(1):56. Lancet 2-10-1979;1(8111):319. Effects of glycyrrhizin on biochemical tests in patients with chronic hepatitis -- double blind trial. 2017 Apr 1;27(2):150-154. doi: 10.1684/ejd.2016.2946. White peony root is very much essential and used in Chinese medicine because of its medicinal properties. J Ethnopharmacol 2002;81:101-4.. View abstract. Lee, I. T., Lee, W. J., Tsai, C. M., Su, I. J., Yen, H. T., and Sheu, W. H. Combined extractives of red yeast rice, bitter gourd, chlorella, soy protein, and licorice improve total cholesterol, low-density lipoprotein cholesterol, and triglyceride in subjects with metabolic syndrome. Lee, C. H., Park, S. W., Kim, Y. S., Kang, S. S., Kim, J. Effect of Shakuyaku-kanzo-to (Tsumura TJ-68) on muscle cramps accompanying cirrhosis in a placebo-controlled double-blind parallel study. Cinatl J, Morgenstern B, Bauer G, et al. View abstract. Pfeifer BL, Pirani JF, Hamann SR, Klippel KF. Intern Med 2007;46:575-8. Peony (Paeonia spp). Tooth decay. View abstract. View abstract. Contact Dermatitis 2008;59(1):52. View abstract. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. OTHER NAME(S): Acide Glycyrrhizique, Acide Glycyrrhizinique, Alca. Sontia B, Mooney J, Gaudet L, Touyz RM. Information from this source is evidence-based and objective, and without commercial influence. View abstract. Effect of Shakuyaku-kanzo-to (Tsumura TJ-68) on muscle cramps accompanying cirrhosis in a placebo-controlled double-blind parallel study. Am J Chin Med 2003;31:445-53. . The author has contributed to research in topic(s): Rheum officinale. View abstract. Therapeutic basis of glycyrrhizin on chronic hepatitis B. Antiviral Res 1996;30:171-7. Licorice that has the active ingredient of glycyrrhiza can have serious side effects. Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. Berlango Jimenez A., Jimenez Murillo L., Montero Perez F. J., Munoz Avila J. Clin Rheumatol. Isr J Dent Sci 1989;2(3):153-157. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Am J Epidemiol 2001;153:1085-8. Licorice can cause serious side effects if you take too much of it or use it for too long. View abstract. Eur.Arch.Paediatr.Dent 2010;11(6):274-278. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Lee, S. J., Lee, I. S., and Mar, W. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells. Pharmazie 2010;65(8):624-8. View abstract. MacKenzie, M. A., Hoefnagels, W. H., Jansen, R. W., Benraad, T. J., and Kloppenborg, P. W. The influence of glycyrrhetinic acid on plasma cortisol and cortisone in healthy young volunteers. Medicine (Baltimore) 2018;97(11):e0073. The anti-estrogenic action of beta-glycyrrhetinic acid. Dai DW, Singh I, Hershman JM. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. Hypertension encephalopathy after liquorice ingestion. QJM 2011;104(12):1093-1095. View abstract. Shen, A. Y., Wang, T. S., Huang, M. H., Liao, C. H., Chen, S. J., and Lin, C. C. Antioxidant and antiplatelet effects of dang-gui-shao-yao-san on human blood cells. Hinoshita F, Ogura Y, Suzuki Y, et al. 2020 Dec;58(1):352-356. BMJ Case Rep. 2012 Oct 19;2012. Planta Med 1983;48(5):38-42. Pulmonary edema following a licorice binge. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. This information may not fit your specific health circumstances. Nephron 2002;90:240. Contact Dermatitis 2021;85(4):454-455. View abstract. In an ovarietctomized model, oral administration of a combination of white peony and licorice increased DHEA and serum estrogen concentration. Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis. A. A specific type of peony product, total glucosides of peony (TGP), has most often been used by adults in doses of 600 mg by mouth three times daily for up to 24 weeks. Can J Cardiol 2009;25(10):e357-e358. Some research suggests that licorice extract may help kill bacteria in the mouth that cause tooth decay. Peters, M. C., Tallman, J. 1988;8(11):660-2, 645. Endocrinol Jpn 1991;38(2):167-174. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Ann Clin Biochem 2007;44(Pt 4):397-399. Petramfar P, Hajari F, Yousefi G, Azadi S, Hamedi A. Efficacy of oral administration of licorice as an adjunct therapy on improving the symptoms of patients with Parkinson's disease, A randomized double blinded clinical trial. Note: Results may vary from person to person, depending on the skin type. Licorice is available in many different types of products, including candies, lozenges, teas, chewing, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Side effects in people after breathing tube removal. Kim, H. J., Chang, E. J., Bae, S. J., Shim, S. M., Park, H. D., Rhee, C. H., Park, J. H., and Choi, S. W. Cytotoxic and antimutagenic stilbenes from seeds of Paeonia lactiflora. Middle East J Anaesthesiol. Features : Herbal Energy & Performance: Bronson's Korean Panax Ginseng provides 1000 MG per serving to naturally support energy and physical performance without any unwanted jitters. van den Bosch AE, van der Klooster JM, Zuidgeest DM, et al. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. View abstract. Digestion 2004;69:45-52. Badr, A. E., Omar, N., and Badria, F. A. Am.J Chin Med 2004;32(4):569-578. A dose of 800 milligrams (mg) or more of licorice root per day has been linked to low potassium levels. Bronson Korean Panax Ginseng 1000 mg Supports Energy, Endurance & Vitality + Memory and Mental Performance, 120 Capsules. Burgess, J. J Neuroophthalmol. Moghadamnia, A. J Biol Response Mod 1985;4:551-84. Luper, S. A review of plants used in the treatment of liver disease: part two. The U.S. Food and Drug . [RETRACTED]. Paeonia lactiflora (Chinese peony) and Paeonia brownii (California peony) relax smooth muscle tissue with a particular affinity for the female reproductive tract. . View abstract. Turpie AG, Runcie J, Thomson TJ. Indian J Med Res 1993;98:69-74. Hataya Y, Oba A, Yamashita T, Komatsu Y. Hyponatremia in an elderly patient due to isolated hypoaldosteronism occurring after licorice withdrawal. Further studies on the mechanism of the mineralocorticoid action of licorice in humans. Proanthocyanidins, flavonoids, tannins, polysaccharides, and paeoniflorin are all considered to contribute to the medicinal activity of various forms of peony. Alt Med Rev 2001;6:495-9. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(12):1121-1123. Effects of mouthwash interventions on xerostomia and unstimulated whole saliva flow rate among hemodialysis patients: a randomized controlled study. Wu G, Wu N, Li T, et al. Mechanisms by which Hange-shashin-to reduces prostaglandin E2 levels. Life Sci 1993;53(5):PL63-8. View abstract. May Harm Baby During Pregnancy. Hajiaghamohammadi, A. Some sources claim that it's contraindicated during pregnancy . View abstract. Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. Title 21. Steinberg, D., Sgan-Cohen, H. D., Stabholz, A., Pizanty, S., Segal, R., and Sela, M. N. The anticariogenic activity of glycyrrhizin: preliminary clinical trials. Chemical studies of Chinese licorice-roots. Altern Med Rev 1999;4(3):178-188. Ou TT, Wu CH, Hsu JD, et al. J Clin Psychopharmacol 2008;28(3):264-370. [13] A study in Japan compared the use of a . This information may not fit your specific health circumstances. Int J Environ Res Public Health 2021;19(1):242. Ruiz-Granados, E. S., Shouls, G., Sainsbury, C., and Antonios, T. A salty cause of severe hypertension. View abstract. Zong, P. P., Yan, T. Y., and Gong, M. M. [Clinical and experimental studies of effects of huayu decoction on scavenging free radicals]. Taking peony along with medications that also slow blood clotting might increase the risk of bruising and bleeding. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Ha Y, Wang T, Li J, et al. View abstract. Yamaguchi, H., Kidachi, Y., Kamiie, K., Noshita, T., Umetsu, H., and Ryoyama, K. Glycyrrhetinic acid induces anoikis-like death and cytoskeletal disruption in the central nervous system tumorigenic cells. Biofactors 2009;35(1):98-104. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(4):358-360. J Pharmacobiodyn 1983;6:153-60. . View abstract. Life Sci 1994;55(11):863-872. (Doses up to 60 grams daily for up to 4 months have been used without reported adverse effects.) A double-blind, randomized, placebo-controlled, multicenter trial. Armanini D, De Palo CB, Mattarello MJ, et al. Taking licorice and loop diuretics together might make potassium levels drop too low. White Peony Tea Side Effects. Antiviral Res 1989;11(5-6):255-261. The dogs treated with the herbal mixture saw a 37.5 percent improvement . The combination of Licorice and Peony has been used in TCM for centuries and now used extensively in western herbal medicine for ovarian cysts and PCOS. 2011;25(2):312-313. View abstract. View abstract. Reuter, J., Merfort, I., and Schempp, C. M. Botanicals in dermatology: an evidence-based review. View abstract. 17. Because of its beneficial effects, the licorice root has been dubbed the "Medicinal plant of 2012." Now scientists have discovered that licorice root from the papilionaceae or leguminous family . 2004;4(3):377-386. Cumming, A. M., Boddy, K., Brown, J. J., Fraser, R., Lever, A. F., Padfield, P. L., and Robertson, J. I. View abstract. Biol Pharm Bull. Phytother Res 2008;22(2):141-148. View abstract. J Assoc Physicians India 1989;37(10):647. View abstract. View abstract. View abstract. Kondo K1, Shiba M, Nakamura R, Morota T, Shoyama Y. Electronic Code of Federal Regulations. View abstract. Decreasing the effects of warfarin might increase the risk of clotting. View abstract. The benefits of licorice root can be enjoyed as a tea, supplement, tincture, or topical treatment, and even as candies. White peony ( bai shao in Chinese) is root without any bark, while red peony . View abstract. View abstract. Yorgun, H., Aksoy, H., Sendur, M. A., Ates, A. H., Kaya, E. B., Aytemir, K., and Oto, A. Brugada syndrome with aborted sudden cardiac death related to liquorice-induced hypokalemia. Int J Nurs Stud 2016;63:9-17. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Nutrition 2002;18(3):268-273. [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. View abstract. Guo, T. L. and Zhou, X. W. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. View abstract. View abstract. Sakamoto S, Kudo H, Suzuki S, et al. [Paeonia Lactiflora injection in treating chronic cor pulmonale with pulmonary hypertension]. View abstract. This week, The New England Journal of Medicine reported that a man with a poor diet died of cardiac arrest after eating a bag-and-a-half of black licorice daily for weeks. View abstract. Moreover, it will be necessary to check for recurrence . J Clin Psychopharmacol 1997;17(3):234-235. Preterm birth and licorice consumption during pregnancy. Aliment Pharmacol Ther 2004;20:1279-87. Fatal hypokalaemic alkalosis with tetany during liquorice and P.A.S. View abstract. Okubo T, Nagai F, Seto T, et al. Lipids Health Dis 2011;10:29. View abstract. Food Chem Toxicol 1993;31:303-12. View abstract. View abstract. Rackova, L., Jancinova, V., Petrikova, M., Drabikova, K., Nosal, R., Stefek, M., Kostalova, D., Pronayova, N., and Kovacova, M. Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin. View abstract. View abstract. . View abstract. Licorice is an herb that grows in parts of Europe and Asia. 10. Side effects of peony tea! Crean, A. M., Abdel-Rahman, S. E., and Greenwood, J. P. A sweet tooth as the root cause of cardiac arrest. Armanini, D., Mattarello, M. J., Fiore, C., Bonanni, G., Scaroni, C., Sartorato, P., and Palermo, M. Licorice reduces serum testosterone in healthy women. View abstract. Lee, S. M., Li, M. L., Tse, Y. C., Leung, S. C., Lee, M. M., Tsui, S. K., Fung, K. P., Lee, C. Y., and Waye, M. M. Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway. J Clin Periodontol 1991;18(3):210-212. Fortschr.Med 7-30-1992;110(21):395-398. . Ir J Med Sci 2016;185(4):945-7. Nat Prod Res 2007;21(14):1234-1241. View abstract. 2020;247:112226. 2013 Sep;117(3):614-21. Zheng, A. and Moritani, T. Effect of the combination of ginseng, oriental bezoar and glycyrrhiza on autonomic nervous activity and immune system under mental arithmetic stress. Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism. Licorice is Sita (cold) in nature, Guru (heavy) to digest, and Madhura (sweet) in . The effect of a traditional Chinese prescription for a case of lung carcinoma. View abstract. Indian J Dent Res 2010;21(3):380-384. About Dr.Cope. View abstract. View abstract. Epilepsy Res 2021;176:106735. This is a partial list of herbs and herbal treatments with known or suspected adverse effects, either alone or in interaction with other herbs or drugs.Non-inclusion of an herb in this list does not imply that it is free of adverse effects. Taking peony along with birth control pills might increase the risk of side effects. View abstract. J Nutr Sci Vitaminol. Cardiovasc.Drugs Ther 1998;12(6):599-600. Liang, R. N., Liu, J., and Lu, J. A., Torres Murillo J., and Calderon de la Barca Gazquez J. M. [Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. Nippon Rinsho 1994;52:1817-22. Gut 1978;19(9):779-782. J Am Acad Dermatol 2011;65(4):699-714. therapy. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . View abstract. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. View abstract. A., Braun, T. M., and Jacobson, J. J. Taking peony root along with phenytoin might decrease the effects of phenytoin and increase the risk of seizures. Korri, H., Awada, A., Baajour, W., Beaini, M., and Nasreddine, W. [Rapidly progressing quadriparesis secondary to licorice (souss) intoxication]. Wilson, J. Evaluation of contextual and demographic factors on licorice effects on reducing hot flashes in postmenopause women. View abstract. Brasseur, A. and Ducobu, J. View abstract. Koo YK, Kim JM, Koo JY, et al. Clin Neurol Neurosurg 1993;95(1):35-37. Here are a few of them: . Neurology 2010;75(21):1939-1941. The roots are commonly used in Traditional Chinese Medicine (TCM) for many purposes. Ann Pharmacother 2003;37(6):836-838. Cooper, H., Bhattacharya, B., Verma, V., McCulloch, A. J., Smellie, W. S., and Heald, A. H. Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease. Yamashiki, M., Nishimura, A., Suzuki, H., Sakaguchi, S., and Kosaka, Y. Ital.J Neurol.Sci 1997;18(4):217-220. Oral Dis 2012;18(1):32-39. Rosenblat, M. and Aviram, M. Paraoxonases role in the prevention of cardiovascular diseases. View abstract. Review of over-the-counter treatments for aphthous ulceration and results from use of a dissolving oral patch containing glycyrrhiza complex herbal extract. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. View abstract. Prieto JM, Recio MC, Giner RM, et al. 1986;6(12):714-6, 707. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. [Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis]. Aging Clin Exp Res. It's thought liquorice's side-effects are caused by the glycyrrhizic acid, but it is possible to buy deglycyrrhizinated liquorice (DGL), which may help prevent these issues. Lee YS, Lorenzo BJ, Koufis T, et al. Koster, M. and David, G. K. Reversible severe hypertension due to licorice ingestion. Jia, Y. Deglycyrrhizinated liquorice in duodenal ulcer. Menati L, Khaleghinezhad K, Tadayon M, Siahpoosh A. J Hypertens 1985;3(1):19-23. Br J Dermatol 1992;126:179-84. Postgrad Med 2017;129(3):329-31. View abstract. J Contemp Dent Pract 2010;11(1):E088-E094. Goto, F., Asama, Y., and Ogawa, K. Sho-saiko-to-ka-kikyo-sekko as an alternative treatment for chronic tonsillitis to avoid surgery. Dehours E, Vall B, Roug-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. Sucking on a licorice lozenge or gargling with a licorice fluid shortly before placement of a breathing tube seems to help prevent cough and. Medicinal uses of licorice through the millennia: the good and plenty of it. View abstract. Tu, J. H., He, Y. J., Chen, Y., Fan, L., Zhang, W., Tan, Z. R., Huang, Y. F., Guo, D., Hu, D. L., Wang, D., and Hong-Hao Zhou. A double-blind, randomized, placebo-controlled trial on the effects of an herbal preparation in patients with functional dyspepsia [Abstract]. Part 2: Effect of glycyrrhizic acid on the course of illness]. Coloclyster of Red Peony Root Granules Alleviates Moderately Severe Acute Pancreatitis: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial. J Ethnopharmacol 2004;94:339-44. . If you take birth control pills along with peony, use an additional form of birth control such as a condom. View abstract. Unfortunately, there is not much scientific evidence around the use of Licorice in Hirsutism, and more studies are needed to prove if it's effective in hirsutism or not. J Clin Psychopharmacol 2016;36(6):572-9. Antiviral Res 2003;59(1):41-47. Wang Y, Ma R. [Effect of an extract of Paeonia lactiflora on the blood coagulative and fibrinolytic enzymes]. Licorice might increase blood pressure. Planta Med 2003;69(12):1113-1118. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. Int Immunopharmacol 2012;14(1):27-31. J Clin Pharm Ther 2001;26:271-8. Liquorice-induced rise in blood pressure: a linear dose-response relationship. Schleimer, R. P. Potential regulation of inflammation in the lung by local metabolism of hydrocortisone. Some medications are changed and broken down by the liver. 2013 Jun;22(2):173-8. View abstract. View abstract. Luo, Y. G., Liu, Y. Q., and Hu, J. Lancet 1992;340:13-17. J Altern Complement Med. Tacconi, P., Paribello, A., Cannas, A., and Marrosu, M. G. Carpal tunnel syndrome triggered by excessive licorice consumption.